abstract：:The activity of dipeptidyl peptidase IV (DPP IV) was measured in the serum and peripheral blood mononuclear cells (MNC) of patients with systemic lupus erythematosus (SLE). The number of DPP IV positive (DPP IV+) lymphocytes in blood smears was determined cytochemically in groups of patients with active, moderate and ...

journal_title：Clinical and experimental rheumatology

authors： Stancíková M,Lojda Z,Lukác J,Ruzicková M

更新日期：1992-07-01 00:00:00

abstract：:A series of different ultrasonographic abnormalities detected by salivary gland echography (SGE) were investigated for their discriminant power for Sjögren's syndrome (SS) in 53 patients with either primary SS (n = 27) or secondary SS (n = 26), as well as in 90 controls. Among the controls, 26 suffered from dry mouth ...

journal_title：Clinical and experimental rheumatology

authors： De Vita S,Lorenzon G,Rossi G,Sabella M,Fossaluzza V

更新日期：1992-07-01 00:00:00

abstract：:Hypertrophic osteoarthropathy (HOA) was first described in 1868 as "hyperostosis of the entire skeleton". It has also been mistaken for acromegaly. In 1887-1888 the first description was given of a dermatological disorder "cutis verticis girata" which coexisted with the peculiar bone anomalies of HOA. In 1890 HOA was ...

journal_title：Clinical and experimental rheumatology

authors： Carcassi U

更新日期：1992-05-01 00:00:00

abstract：:In an unselected population of 1390 consecutive Albanian patients with rheumatic diseases (RD) and other miscellaneous non-rheumatic diseases (MNRD), for whom antinuclear antibody (ANA) testing was requested, we calculated the diagnostic sensitivity, specificity and positive predictive value (PPV) of ANA positive resu...

journal_title：Clinical and experimental rheumatology

authors： Sulcebe G,Morcka K

更新日期：1992-05-01 00:00:00

abstract：:This review considers the epidemiological aspects of the genetic investigation of rheumatoid arthritis (RA). Problems both of disease definition and disease heterogeneity render studies difficult to undertake and interpret. The selection of individuals both in population and family studies can explain divergent result...

journal_title：Clinical and experimental rheumatology

authors： Silman AJ

更新日期：1992-05-01 00:00:00

abstract：:A 57-year-old female patient presented with a tenosynovitis due to Mycobacterium avium-intracellulare (MAI). A relapse occurred following surgical treatment, after which she was successfully treated with ansamycin and ethambutol. Previously reported cases of tenosynovitis due to MAI are reviewed and the treatment moda...

journal_title：Clinical and experimental rheumatology

authors： Eggelmeijer F,Kroon FP,Zeeman RJ,Dijkmans BA,van 't Wout JW

更新日期：1992-03-01 00:00:00

abstract：:The enhanced platelet reactivity and impaired thrombolysis in patients with systemic sclerosis may contribute to the microvascular insufficiency seen in this disease. Anti-platelet therapy has therefore been suggested for the treatment of Raynaud's phenomenon secondary to systemic sclerosis. Using a novel technique, t...

journal_title：Clinical and experimental rheumatology

authors： Rademaker M,Meyrick Thomas RH,Kirby JD,Kovacs IB

更新日期：1992-01-01 00:00:00

abstract：:We report a retrospective study of 17 patients with systemic lupus erythematosus who were treated with oral methotrexate given as a mean weekly dose of 8.47 +/- 1.72 mg. Methotrexate treatment resulted in symptomatic improvement in 57% of patients and allowed the reduction of the mean daily dose of prednisone from 16....

journal_title：Clinical and experimental rheumatology

authors： Wilke WS,Krall PL,Scheetz RJ,Babiak T,Danao T,Mazanec DJ,Segal AM,Clough JD

更新日期：1991-11-01 00:00:00

abstract：:Recognition that the lupus anticoagulant (LA) is associated with an increased risk for arterial and venous thrombosis, recurrent spontaneous abortions and fetal loss has led to increased laboratory requests for identification of LA. It is of interest not only to laboratory medicine and obstetrics but also to rheumatol...

journal_title：Clinical and experimental rheumatology

authors： Barna LK,Triplett DA

更新日期：1991-11-01 00:00:00

abstract：:An analysis is presented of 20 patients with the human immunodeficiency virus (HIV) infection who were treated for skeletal infection in our hospital. Seventeen cases of septic arthritis and three of osteomyelitis were found. All patients were intravenous drug abusers, 75% were male and all were younger than 40 years ...

journal_title：Clinical and experimental rheumatology

authors： Muñoz Fernandez S,Quiralte J,del Arco A,Balsa A,Cardenal A,Peña JM,Vazquez JJ,Gijón Baños J

更新日期：1991-09-01 00:00:00

abstract：:Antibodies against bromelain-treated erythrocytes occurring in normal mice are germline gene-encoded IgM natural autoantibodies that are secreted by CD5+ B cells, and react primarily with phosphatidylcholine (PTC), but may crossreact with cardiolipin (aCL). Some of the IgM antiphospholipid antibodies (aPL) present in ...

journal_title：Clinical and experimental rheumatology

authors： Velasquillo MC,Alcocer-Varela J,Alarcón-Segovia D,Cabiedes J,Sánchez-Guerrero J

更新日期：1991-09-01 00:00:00

abstract：:In a patient (BAR) affected by chronic active hepatitis we isolated a cryoglobulin constituted of polyclonal IgM (k and lambda) and a monoclonal IgG3 lambda. The IgM represented the antibody of the cryoglobulin complex. This type of cryoglobulin, where the monoclonal component is the antigen and not the antibody, cann...

journal_title：Clinical and experimental rheumatology

authors： Bellotti V,Zorzoli I,Bossi A,Rancati E,Salvadeo A,Merlini G

更新日期：1991-07-01 00:00:00

abstract：:The prevalence of primary Sjögren's syndrome (primary SS) among patients with autoimmune thyroiditis (AT), and that of AT among patients with primary SS were studied prospectively. Of 63 patients with AT, one had precipitating antibodies against SS-A/Ro antigen together with objectively verified primary SS, and none h...

journal_title：Clinical and experimental rheumatology

authors： Hansen BU,Ericsson UB,Henricsson V,Larsson A,Manthorpe R,Warfvinge G

更新日期：1991-03-01 00:00:00

abstract：:The objectives of this study were: first, to determine the platelet morphology in the peripheral circulation of patients with cyanotic congenital heart diseases and thus its possible link to the development of hypertrophic osteoarthropathy. Second: to test the mathematical model which proposes that in normal individua...

journal_title：Clinical and experimental rheumatology

authors： Vazquez-Abad D,Martinez-Lavin M

更新日期：1991-01-01 00:00:00

abstract：:Leg ulcers are associated with antiphospholipid antibodies in patients with systemic lupus erythematosus. They may also occur in patients with primary antiphospholipid syndrome(PAPS). Histopathologic findings at the edges of the ulcers may give insight into their pathogenesis. In a patient with PAPS and a leg ulcer, a...

journal_title：Clinical and experimental rheumatology

authors： Reyes E,Alarcon-Segovia D

更新日期：1991-01-01 00:00:00

abstract：:Ankylosing spondylitis (A.Sp.) and diffuse idiopatic skeletal hyperostosis (DISH), represent the most common inflammatory and degenerative enthesopathies, respectively. Despite their rather frequent occurrence in the rheumatic disease care setting, few case reports of their simultaneous presence in the same patient ha...

journal_title：Clinical and experimental rheumatology

authors： Troise Rioda W,Ferraccioli GF

更新日期：1990-11-01 00:00:00

abstract：:Different tools are available for the measurement of functional status; however, only a few of them are based on the evaluation of the joint range of motion (ROM). This study is aimed at the design and evaluation of the measurement properties of a ROM scale to be used as an evaluative instrument in rheumatoid arthriti...

journal_title：Clinical and experimental rheumatology

authors： Ferraz MB,Oliveira LM,Araujo PM,Atra E,Walter SD

更新日期：1990-09-01 00:00:00

abstract：:Sjögren's syndrome is a multifactorial disease in which genetic and possibly viral factors play major roles. The recent development of an SS-like disease in patients infected with HIV-1 suggests a possible retrovirus. ...

journal_title：Clinical and experimental rheumatology

authors： Talal N

更新日期：1990-07-01 00:00:00

abstract：:Serum levels of the aminoterminal type III procollagen peptide (S-PIIINP) have been used as markers of proliferative inflammation in rheumatoid arthritis (RA) and a prognostic significance has been suggested. To test this further we have measured S-PIIINP longitudinally for 2 years in 66 patients with definite RA and ...

journal_title：Clinical and experimental rheumatology

authors： Eberhardt K,Thorbjorn Jensen L,Horslev-Petersen K,Pettersson H,Lorenzen I,Wollheim F

更新日期：1990-07-01 00:00:00

abstract：:Heat shock proteins (hsp) or "stress proteins" are a group of highly conserved proteins which are important in the day to day function of all cells. Early studies by others have indicated that immunity to the 65 kDa hsp of mycobacteria is important in the development of arthritis in the adjuvant arthritis model in rat...

journal_title：Clinical and experimental rheumatology

authors： Lydyard PM,Tsoulfa G,Sharif M,Bröker B,Smith M,Rook GA

更新日期：1990-07-01 00:00:00

abstract：:Pediatric research has been limited regarding the neuropsychologic status in systemic lupus erythematosus (SLE) despite frequent involvement of the central nervous system early in the disease process. SLE is a multisystem autoimmune disorder which often presents with significant neuropsychiatric manifestations includi...

journal_title：Clinical and experimental rheumatology

authors： Papero PH,Bluestein HG,White P,Lipnick RN

更新日期：1990-07-01 00:00:00

abstract：:There is increasing evidence supporting the involvement of Leu 1+B cells in the development of human autoimmune diseases. In this study, the frequency of Leu 1+B cells has been analysed by a multiparameter FACS machine in newborn cord blood, and in the peripheral blood of several autoimmune patients and their healthy ...

journal_title：Clinical and experimental rheumatology

authors： Kazbay K,Osterland CK

更新日期：1990-05-01 00:00:00

abstract：:In order to study local immunoregulatory mechanisms in patients with seronegative spondylarthropathy and histological evidence of asymptomatic intestinal inflammation, we determined mononuclear cells in distal ileal mucosa with an indirect immunoperoxidase technique using a panel of monoclonal antibodies. The number o...

journal_title：Clinical and experimental rheumatology

authors： Cuvelier C,Dierick AM,Mielants H,De Vos M,Veys E,Roels H

更新日期：1990-03-01 00:00:00

abstract：:Monoclonal antibody against c-myc protein was used in the avidin-biotin-peroxidase complex procedure to examine frozen sections of psoriatic and normal skin and psoriatic synovium for the presence of c-myc protein. A significantly greater percentage (88%) of epithelial cells from psoriatic skin lesions stained for c-m...

journal_title：Clinical and experimental rheumatology

authors： Osterland CK,Wilkinson RD,St Louis EA

更新日期：1990-03-01 00:00:00

abstract：:To test whether alternative complement pathway activation explains normal C1s-C1 inhibitor complex in hypocomplementemic (low CH50cl) patients with systemic lupus erythematosus, we examined alternative pathway hemolytic complement (CH50alt) factor B, and Ba fragment in hypocomplementemic sera with normal and with elev...

journal_title：Clinical and experimental rheumatology

authors： Levy RA,Qamar T,Lockshin MD

更新日期：1990-01-01 00:00:00

abstract：:An immunological imbalance is probably one of the major pathogenetic causes of rheumatoid arthritis in adults as well as in children. This aspect is the rationale for the use of immuno-modulating drugs. In our study we evaluated the effects of intravenously-administered thymopentin on systemic and local features in 10...

journal_title：Clinical and experimental rheumatology

authors： Bardare M,Corona F,Ogliari MT,Cohen E

更新日期：1990-01-01 00:00:00

abstract：:Offspring of a cross between the NZB and NZW mice (F1) develop a disease similar to SLE in humans. Female mice of the F1 strain develop the disease at a younger age and die earlier than the males. In order to test the hypothesis that estrogen receptor concentrations in the lymphoid organs of these mice may correlate w...

journal_title：Clinical and experimental rheumatology

authors： Athreya BH,Moore WC,Wadsworth SA,Gupta C,Goldman AS

更新日期：1989-11-01 00:00:00

abstract：:In a clinical study the blood levels of dehydroepiandrosterone sulphate (DHEAS), pregnenolone sulphate (5-PS), testosterone sulphate (TS) and their respective unconjugated steroids were measured in: 20 patients with systemic lupus erythematosus (SLE) who were receiving either no treatment (11 patients) or else treatme...

journal_title：Clinical and experimental rheumatology

authors： Hedman M,Nilsson E,de la Torre B

更新日期：1989-11-01 00:00:00

abstract：:Anti-phospholipids represent a heterogeneous family of antibodies able to react with the negatively charged phosphodiester groups of phospholipids. It includes the antibodies directed against the cardiolipin moiety of the VDRL antigen, the antibodies reacting with the phospholipids of the prothrombin activator complex...

journal_title：Clinical and experimental rheumatology

authors： Meroni PL,Tincani A,Harris EN,Valesini G,Hughes GR,Balestrieri G

更新日期：1989-09-01 00:00:00

abstract：:A Cambodian man and his son concomitantly developed malignant Reiter's syndrome soon after their arrival in France. In both cases generalized skin lesions of pustular psoriasis and systemic features were present. The son died after 2 years of unresponsive continuously progressive disease. The father received pulses of...

journal_title：Clinical and experimental rheumatology

authors： Wattiaux MJ,Bourgeois P,Picard O,Bennani M,Thomas M,Desproges-Gotteron R,Kahn MF,Imbert JC

更新日期：1989-09-01 00:00:00

abstract：:Surgical treatment of rheumatoid arthritis dates back some fifty years to when rheumatology developed into a separate branch of medicine. An interdisciplinary approach to rheumatoid arthritis was then introduced at a few specialized centres. By refining the surgical techniques, increasing the number of surgical option...

journal_title：Clinical and experimental rheumatology

authors： Rinonapoli E

更新日期：1989-09-01 00:00:00

abstract：:The type II collagen induced arthritis animal model (CIA) provides opportunities to study the nature of autoimmune reactions leading to arthritis and is also a useful model for rheumatoid arthritis (RA). Thus, in similarity with RA, the CIA when induced with autologous type II collagen, shows a chronic and progressive...

journal_title：Clinical and experimental rheumatology

authors： Holmdahl R,Mo J,Nordling C,Larsson P,Jansson L,Goldschmidt T,Andersson M,Klareskog L

更新日期：1989-09-01 00:00:00

abstract：:This article reviews the rheumatic manifestation of the immune deficiency disorders. In particular, the rheumatic manifestations of hypogammaglobulinaemia and the acquired immune deficiency syndrome (AIDS) are discussed. ...

journal_title：Clinical and experimental rheumatology

authors： Preston SJ,Buchanan WW

更新日期：1989-09-01 00:00:00

abstract：:This study examines the interrelationship between arachidonic acid (AA) metabolism and chemotactic potential of human peripheral blood neutrophils from both normal donors and patients with rheumatoid arthritis (RA). We demonstrate that there is a significant inverse relationship between the neutrophil's metabolic capa...

journal_title：Clinical and experimental rheumatology

authors： Smith DM,Johnson JA,Turner RA

更新日期：1989-09-01 00:00:00

abstract：:Skin biopsies from 4 systemic sclerosis (SSc) patients, 6 SSc patients treated with D-penicillamine (from 8 to 60 months) and 4 normal subjects were analyzed by light and electron microscopy. By light microscopy, collagen bundles of SSc dermis were thicker and more compact than in age-matched controls; D-penicillamine...

journal_title：Clinical and experimental rheumatology

authors： Pasquali Ronchetti I,Guerra D,Quaglino D Jr,Vincenzi D,Manzini E,Canossi B,Manzini CU

更新日期：1989-07-01 00:00:00

abstract：:Prostaglandin (PG)E2, cyclic adenosine monophosphate (cAMP), white blood cells (WBC), total protein (TP), total complement activity (CH50) and beta-2-microglobulin (beta-2-m) were measured at baseline and after eight days in the synovial fluid (SF) of 16 patients affected with knee-joint effusion due to various arthro...

journal_title：Clinical and experimental rheumatology

authors： Punzi L,Schiavon F,Cavasin F,Ramonda R,Gambari PF,Todesco S

更新日期：1989-05-01 00:00:00

abstract：:We have followed a community-based cohort of recent-onset arthritis for eight years. In addition to Waaler-Rose and latex agglutination tests we used class-specific enzyme immunoassay for the determination of rheumatoid factors (RFs). Eighty-seven patients had erosions by the end of the follow-up period. The seroposit...

journal_title：Clinical and experimental rheumatology

authors： Aho K,Tuomi T,Palosuo T,Kaarela K,Von Essen R,Isomäki H

更新日期：1989-05-01 00:00:00

abstract：:A young female patient who had documented seropositive rheumatoid arthritis and was treated consecutively with aspirin, diclofenac, and gold salts was admitted years later for severe neutropenia. On examination she had, in addition, fever, positive rheumatoid factor, reversible swan-neck deformity of the fingers but o...

journal_title：Clinical and experimental rheumatology

authors： Cycowitz Z,Heller I,Burke M,Vardinon N,Yust I

更新日期：1989-05-01 00:00:00

abstract：:33 patients with scleroderma, xerostomia and xerophthalmia underwent biopsy of 3 to 5 labial salivary glands. Histological and ultrastructural study were systematically performed on the salivary gland specimen. In 27 patients, sclerosis was the main feature: it was an active fibrosis, with numerous secreting fibroblas...

journal_title：Clinical and experimental rheumatology

authors： Janin A,Gosselin B,Gosset D,Hatron PY,Sauvezie B

更新日期：1989-03-01 00:00:00

abstract：:Primary fibromyalgia syndrome (PFS) is a common form of nonarticular rheumatism with chronic and generalized musculoskeletal aching and stiffness, accompanied by tender points at characteristic sites in the absence of an underlying condition. No satisfactory criteria for its diagnosis, based on appropriate controlled ...

journal_title：Clinical and experimental rheumatology

authors： Yunus MB,Masi AT,Aldag JC

更新日期：1989-01-01 00:00:00